1309955-14-3Relevant articles and documents
Rational Design of Cell-Active Inhibitors of PARP10
Morgan, Rory K.,Kirby, Ilsa T.,Vermehren-Schmaedick, Anke,Rodriguez, Kelsie,Cohen, Michael S.
, p. 74 - 79 (2019/01/04)
Poly-ADP-ribose polymerases (PARPs 1-16) have emerged as major regulators of diverse cellular processes. PARPs can be subclassified based on their ability to catalyze poly-ADP-ribosylation (PARylation) or mono-ADP-ribosylation (MARylation). While much is
Aromatic ring functionalization of benzolactam derivatives: New potent dopamine D3 receptor ligands
Ortega, Raquel,Hübner, Harald,Gmeiner, Peter,Masaguer, Christian F.
, p. 2670 - 2674 (2011/06/20)
Since the discovery of the dopamine D3 receptor, an intensive effort has been directed toward the development of potent and selective ligands in order to elucidate the function and potential therapeutic advantages of targeting D3 rec