1309962-07-9Relevant academic research and scientific papers
A formal synthesis of antimalarial diterpenoid 7,20-diisocyanoadociane
Miyaoka, Hiroaki,Okubo, Yusuke,Muroi, Makiko,Mitome, Hidemichi,Kawashima, Etsuko
, p. 246 - 247 (2011)
A formal synthesis of antimalarial diterpenoid 7,20-diisocyanoadociane, isolated from marine sponge Adocia sp., was achieved. The authors synthesized Corey's synthetic intermediate 2 for 7,20-diisocyanoadociane. This synthesis involves the synthesis of a perhydropyrene derivative using a sequential isomerizationintramolecular DielsAlder reaction as the key step.
