1309965-19-2Relevant academic research and scientific papers
Hydroxylation of anilides by engineered cytochrome P450BM3
O'Hanlon, Jack A.,Ren, Xinkun,Morris, Melloney,Wong, Luet Lok,Robertson, Jeremy
supporting information, p. 8780 - 8787 (2017/11/03)
Biocatalytic direct monohydroxylation of anilides has been achieved on preparative scale using mutant cytochrome P450BM3 enzymes. Representative mono- and disubstituted N-trifluoromethanesulfonyl anilides are shown to be converted in most cases to the corresponding 4-hydroxy derivatives, with substituent hydroxylation also occurring in two cases. By mutation variation, it is possible to achieve selective hydroxylation of either ring- or side-chain sites.
Synthesis and thiocyanation of N-Alkyl(trifluoromethyl)sulfonyl 1,4-benzoquinone monoimines
Avdeenko,Konovalova,Mikhailichenko,Shelyazhenko,Pirozhenko,Yagupol'skii
experimental part, p. 510 - 519 (2011/07/29)
New N-alkyl(trifluoromethyl)sulfonyl 1,4-benzoquinone monoimines were synthesized, and their thiocyanation gave 5-alkyl(trifluoromethyl)sulfonylamino- 1,3-benzoxathiol-2-ones. An intermediate thiocyanation product, 5-trifluoromethylsulfonylamino-1,3-benzo
