1310024-95-3Relevant academic research and scientific papers
Umbelliferone-oxindole hybrids as novel apoptosis inducing agents
Nagarsenkar, Atulya,Guntuku, Lalita,Prajapti, Santosh Kumar,Guggilapu, Sravanthi Devi,Sonar, Rajkiran,Vegi, Ganga Modi Naidu,Babu, Bathini Nagendra
, p. 12604 - 12610 (2017)
In furtherance of our endeavour towards the synthesis of novel bioactive agents, a panel of (E)-3-((7-hydroxy-4-methyl-2-oxo-2H-chromen-8-yl)methylene)indolin-2-one derivatives were synthesized using diverse 5-substituted oxindoles and 7-hydroxy-4-methyl-
Zinc Triflate Catalyzed C-Benzylation: Chemo- and Regioselective Route to Amido Substituted Diaryl and Arylheteroarylmethanes
Deshmukh, Mahesh Subhashrao,Srivastava, Ananya,Das, Biswajit,Jain, Nidhi
, p. 10041 - 10048 (2015/11/03)
An unprecedented zinc triflate catalyzed selective C-benzylation of anilides and heteroaryl amides with benzyl chlorides having electron-donating group at para-position is reported. The protocol offers moderate to high yield of para-amido substituted diaryl and arylheteroarylmethanes, uses cheap and easily available benzyl chlorides as the benzylating agent, catalytic amount of zinc triflate, and takes place under ambient conditions. Aminodiarylmethane derivatives can be obtained by hydrolysis of the corresponding amides. The methodology has also been applied for preparing dimethoxydiarylmethanes in good yields, which are the key precursors for synthesis of phenolic natural products.
A novel acid-catalyzed C5-alkylation of oxindoles using alcohols
Reddy, Chada Raji,Jithender, Enukonda,Krishna, Gaddam,Reddy, Gunreddy Venkat,Jagadeesh, Bharatam
experimental part, p. 3940 - 3947 (2011/06/21)
A novel C5-alkylation of oxindoles using alcohols as alkylating agents under acid catalysis is described for the first time. The reactions of various benzylic, allylic and propargylic alcohols are studied to obtain the corresponding 5-substituted oxindoles in good yields.
