131007-89-1Relevant academic research and scientific papers
Sulfur-containing heterocyclic compounds useful for the treatment of osteoporosis, and their production
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, (2008/06/13)
The present invention provides a sulfur-containing heterocyclic compound of the formula (I) STR1 wherein ring A is a benzene ring which may be substituted; R is a hydrogen atom or a hydrocarbon group which may be substituted; B is a carboxyl group which may be esterified or amidated; X is --CH(OH)-- or --CO--; k is 0 or 1; and k' is 0, 1 or 2 or a pharmaceutically acceptable salt thereof. Also, it provides a process for producing the compound (I) or a salt thereof and a pharmaceutical preparation for use in the treatment of osteoporosis comprising the compound (I) or salt thereof. The compounds (I) and salts thereof show excellent bone resorption inhibitory activity.
