131012-96-9Relevant academic research and scientific papers
Squalene synthetase inhibitors
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, (2008/06/13)
Compounds of structural formula (I): STR1 are squalene synthestase inhibitors useful in inhibiting the biosynthesis of cholesterol in the treatment of hypercholesterolemia and related disorders.
Novel 5-HT3 antagonists. Indole oxadiazoles.
Swain,Baker,Kneen,Moseley,Saunders,Seward,Stevenson,Beer,Stanton,Watling
, p. 140 - 151 (2007/10/02)
The synthesis and biochemical evaluation of a series of indole oxadiazole 5-HT3 antagonists are described. The key pharmacophoric elements have been defined as a basic nitrogen, a linking group capable of H-bonding interactions, and an aromatic moiety. Th
