1310327-18-4

Basic information

• Product Name: Cbz-N-amido-PEG3-acid
• Synonyms: Cbz-N-amido-PEG3-acid;CBZ-NH-PEG3-propionic acid;CBZ-12-amino-4,7,10-trioxadodecanoic acid;CBZ-AEEEP;CbzNH-PEG3-CH2CH2COOH
• CAS NO: 1310327-18-4
• Molecular Formula: C₁₇H₂₅NO₇
• Molecular Weight: 355.3829
• Mol File: 1310327-18-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Cbz-N-amido-PEG3-acid(CAS DataBase Reference)
• NIST Chemistry Reference: Cbz-N-amido-PEG3-acid(1310327-18-4)
• EPA Substance Registry System: Cbz-N-amido-PEG3-acid(1310327-18-4)

Safety Data

• Hazardous Substances Data: 1310327-18-4(Hazardous Substances Data)

Usage

Description

Cbz-N-amido-PEG3-acid is a PEG linker containing a CBZ-protected amino group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The protected amine can be deprotected by acidic conditions.

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Downstream Products

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Relevant articles and documents

PHENYL TETRAHYDROISOQUINOLINE COMPOUND SUBSTITUTED WITH HETEROARYL

The present invention provides a compound represented by the following formula [1] or a pharmaceutically acceptable salt thereof which has an excellent NHE3 inhibitory effect: ????????[Formula 15]?????A-Y [1] wherein A represents a structure represented b

Synthesis and antibody binding of highly fluorinated amphiphilic MUC1 glycopeptide antigens

The analysis of humoral immune responses is of great importance for basic and clinical research. Mapping the structural requirements of epitope recognition with modified tumor-associated carbohydrate antigens allows both the development of biomarkers and the design of synthetic anticancer vaccines. For this purpose, double-tailed hydrocarbon/fluorocarbon membrane anchors have been prepared and conjugated to a TN dipeptide. Furthermore, a novel hydrophobized MUC1 tandem repeat glycopeptide antigen was fully assembled on a solid support and its specific binding to different mouse anti-MUC1 antibodies was demonstrated through ELISA, QCM, and SPR measurements. Such functional fluorous MUC1 antigens are of great interest for specific glycan (micro-)array formats and allow a detailed analyses of serum antibodies obtained from immunization studies. In addition, the intriguing characteristics of fluorous surfactants, for example, their strong self-association tendency, might stimulate the use of novel fluorous-tagged antigen conjugates in the development of multivalent micellar glycopeptide vaccines. Copyright