131035-50-2

Upstream product

• 7721-62-2 4,5-dimethoxy-2-methylbenzaldehyde 
• 494-99-5 1,2-dimethoxy-4-methylbenzene 

Downstream Products

• 131035-51-3 ethyl 2,3-dibromo-3-(4,5-dimethoxy-2-methylphenyl)propionate 
• 131035-52-4 methyl 3-(4,5-dimethoxy-2-methylphenyl)propiolate 
• 131035-53-5 (4,5-Dimethoxy-2-methyl-phenyl)-propynoic acid 

Relevant academic research and scientific papers

Heterogeneous catalysis with nickel-on-graphite (Ni/Cg): Reduction of aryl tosylates and mesylates

(Chemical Equation Presented) How would you reduce an aryl OH group? Traditionally, a palladium catalyst, a mild source of hydride, and a triflate derivative are used in solution. A more modern alternative is presented that is not only economical but heterogeneous as well. Nickel-on-graphite (Ni/C g) is introduced as a very inexpensive catalyst that reduces aryl tosylates and mesylates with excellent functional group tolerance.

Synthesis based on Cyclohexadienes: Part 4. Novel Synthesis of the 6-Aryl-2,4-dimethoxybenzoates. Alternariol and Methyl Trimethylaltenusin

A novel method for the preparation of 6-aryl-2,4-dimethoxybenzoic acids involving the Alder-Rickert reaction of 1,5-dimethoxycyclohexa-1,4-dienes and arylpropiolic esters is described.This strategy has been extended to the synthesis of the mould metabolite alternariol and methyl trimethylaltenusin.