1310385-02-4Relevant articles and documents
PYRROLOPYRROLONE DERIVATIVES AND THEIR USE AS BET INHIBITORS
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Page/Page column 85; 110; 111; 117, (2015/06/08)
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Cobalt-catalyzed C-H borylation
Obligacion, Jennifer V.,Semproni, Scott P.,Chirik, Paul J.
supporting information, p. 4133 - 4136 (2014/04/03)
A family of pincer-ligated cobalt complexes has been synthesized and are active for the catalytic C-H borylation of heterocycles and arenes. The cobalt catalysts operate with high activity and under mild conditions and do not require excess borane reagents. Up to 5000 turnovers for methyl furan-2-carboxylate have been observed at ambient temperature with 0.02 mol % catalyst loadings. A catalytic cycle that relies on a cobalt(I)-(III) redox couple is proposed.