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1310404-86-4

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1310404-86-4 Usage

General Description

3-((1-(tert-Butoxycarbonyl)piperidin-4-yl)methoxy)phenylboronic acid is a chemical compound with the molecular formula C17H25NO5B. It is a boronic acid derivative that contains a piperidine ring and a phenylboronic acid group. 3-((1-(tert-Butoxycarbonyl)piperidin-4-yl)methoxy)phenylboronic acid is often used as a reagent in organic synthesis and medicinal chemistry, particularly in the development of pharmaceutical compounds. The tert-butoxycarbonyl (Boc) group is a protecting group for amines, allowing for selective manipulation of the molecule during synthesis. The presence of the phenylboronic acid group also allows for the compound to participate in various chemical reactions, such as Suzuki-Miyaura cross-coupling reactions, making it a useful building block in organic synthesis. Overall, 3-((1-(tert-Butoxycarbonyl)piperidin-4-yl)methoxy)phenylboronic acid is a versatile compound with various applications in chemical and pharmaceutical research.

Check Digit Verification of cas no

The CAS Registry Mumber 1310404-86-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,0,4,0 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1310404-86:
(9*1)+(8*3)+(7*1)+(6*0)+(5*4)+(4*0)+(3*4)+(2*8)+(1*6)=94
94 % 10 = 4
So 1310404-86-4 is a valid CAS Registry Number.

1310404-86-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name [3-[[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]methoxy]phenyl]boronic acid

1.2 Other means of identification

Product number -
Other names A-3280

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1310404-86-4 SDS

1310404-86-4Relevant articles and documents

Chemoselective, Scalable Nickel-Electrocatalytic O-Arylation of Alcohols

Baran, Phil S.,Chen, Longrui,Edwards, Jacob T.,Kawamata, Yu,Oderinde, Martins S.,Zhang, Hai-Jun

supporting information, p. 20700 - 20705 (2021/08/17)

The formation of aryl-alkyl ether bonds through cross coupling of alcohols with aryl halides represents a useful strategic departure from classical SN2 methods. Numerous tactics relying on Pd-, Cu-, and Ni-based catalytic systems have emerged over the past several years. Herein we disclose a Ni-catalyzed electrochemically driven protocol to achieve this useful transformation with a broad substrate scope in an operationally simple way. This electrochemical method does not require strong base, exogenous expensive transition metal catalysts (e.g., Ir, Ru), and can easily be scaled up in either a batch or flow setting. Interestingly, e-etherification exhibits an enhanced substrate scope over the mechanistically related photochemical variant as it tolerates tertiary amine functional groups in the alcohol nucleophile.

TREATMENT OF OCULAR DISORDERS

-

, (2014/04/18)

The invention provides methods of treatment of ocular disorders, including ocular disease with an angiogenic component. In certain embodiments, the treatment comprises administration of a ROCK2 inhibitor and an angiogenesis inhibitor. In certain embodiments, the ROCK2 inhibitor is ROCK2 selective. In certain embodiments, the angiogenesis inhibitor is a VEGF antagonist, for example, and VEGFR2 antibody.

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