1310450-08-8

Basic information

• Product Name: C₂₁H₁₉F₂NO
• CAS NO: 1310450-08-8
• Molecular Weight: 339.385
• Mol File: 1310450-08-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₁₉F₂NO(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₁₉F₂NO(1310450-08-8)
• EPA Substance Registry System: C₂₁H₁₉F₂NO(1310450-08-8)

Safety Data

• Hazardous Substances Data: 1310450-08-8(Hazardous Substances Data)

Upstream product

• 16518-64-2 3-(dimethylamino)benzoic acid methyl ester 
• 345-92-6 4,4'-Difluorobenzophenone 

Relevant articles and documents

Development of trityl-based photolabile hydroxyl protecting groups

A series of trityl-based photolabile hydroxyl protecting groups have been examined. These PPGs evolve from the traditional acid-labile trityl protecting group with proper electron-donating substituents. Structure-reactivity relationships have been explored. A m-dimethylamino group is crucial to achieve high photochemical deprotection efficiency. The o-hydroxyl group in 8 greatly improves the yield of the photochemical deprotection reaction, compared with the corresponding o-methoxyl-substituted counterpart 7. However, comparison between the photoreactions of 9 and 11 does not show similar structural relevance. The PPG in ether 1 (i.e., DMATr group) is structurally simple and easy to prepare and install. Its deprotection can be successfully carried out with irradiation of sunlight without requirement of photochemical devices.