1310458-76-4Relevant academic research and scientific papers
Synthesis and biological evaluation of novel 7-acyl homocamptothecins as Topoisomerase I inhibitors
Liu, Wenfeng,Zhu, Lingjian,Guo, Wei,Zhuang, Chunlin,Zhang, Yongqiang,Sheng, Chunquan,Cheng, Pengfei,Yao, Jianzhong,Wang, Wenya,Dong, Guoqiang,Wang, Shengzheng,Miao, Zhenyuan,Zhang, Wannian
, p. 2408 - 2414 (2011/06/22)
A series of novel 7-acyl derivatives of homocamptothecin (hCPT) were designed and synthesized with the purpose to improve antitumor activity of hCPT, via Minisci free-radical reaction from 10-methoxyhomocamptothecin. All the compounds were evaluated for i
