1310487-00-3

Basic information

• Product Name: ((1R,3S)-3-(((S)-2-((tert-butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)-2,2-dimethylcyclopropyl)diphenylmethanol
• CAS NO: 1310487-00-3
• Molecular Weight: 479.778
• Mol File: 1310487-00-3.mol

Chemical Properties

• CAS DataBase Reference: ((1R,3S)-3-(((S)-2-((tert-butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)-2,2-dimethylcyclopropyl)diphenylmethanol(CAS DataBase Reference)
• NIST Chemistry Reference: ((1R,3S)-3-(((S)-2-((tert-butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)-2,2-dimethylcyclopropyl)diphenylmethanol(1310487-00-3)
• EPA Substance Registry System: ((1R,3S)-3-(((S)-2-((tert-butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)-2,2-dimethylcyclopropyl)diphenylmethanol(1310487-00-3)

Safety Data

• Hazardous Substances Data: 1310487-00-3(Hazardous Substances Data)

Upstream product

• 81873-49-6 (1S,2R)-cis-2-methoxycarbonyl-3,3-dimethylcyclopropane-1-carboxylic acid 
• 55701-02-5 methyl (1R,3S)-3-formyl-2,2-dimethylcyclopropanecarboxylate 
• 350699-93-3 (1R,3S)-(-)-2,2-Dimethyl-3-formylcyclopropane-1-carboxylic acid 
• 1310487-06-9 C₂₄H₃₁NO₂ 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 1310487-04-7 (1R,3S)-methyl 3-(((S)-2-(hydroxymethyl)pyrrolidin-1-yl)methyl)-2,2-dimethyl cyclopropanecarboxylate 

Relevant articles and documents

Highly enantioselective addition of trimethylsilylacetylene to aldehydes catalyzed by a zinc-amino-alcohol complex

A fine addition! A highly enantioselective and efficient procedure for the amino-alcohol-zinc-catalyzed addition of trimethylsilylacetylene to aromatic, α,β-unsaturated, and aliphatic aldehydes has been developed (see scheme; R=aryl, alkynyl, or alkyl; TMS=trimethylsilyl; TBDMS=tert- butyldimethylsilyl). The present protocol was successfully applied in the concise synthesis of the natural products marine alkynol and falcarindiol. Copyright