131052-46-5 Usage
Description
C-Thiazol-4-yl-methylamine hydrochloride is a chemical compound characterized by the presence of a thiazole ring and a methylamine group, existing as a hydrochloride salt. It serves as a versatile intermediate in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals, and may also be utilized in other industrial applications as a reagent or building block in chemical reactions.
Uses
Used in Pharmaceutical Industry:
C-Thiazol-4-yl-methylamine hydrochloride is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of novel therapeutic agents. Its unique chemical structure allows for the creation of diverse drug candidates with potential applications in treating various medical conditions.
Used in Agrochemical Industry:
In the agrochemical sector, C-Thiazol-4-yl-methylamine hydrochloride is employed as an intermediate in the production of agrochemicals, such as pesticides and herbicides. Its incorporation into these compounds can enhance their effectiveness in protecting crops and managing pests, thereby contributing to increased agricultural productivity.
Used as a Reagent in Chemical Reactions:
C-Thiazol-4-yl-methylamine hydrochloride also serves as a reagent in various chemical reactions, facilitating the synthesis of complex organic molecules. Its presence can promote specific chemical transformations, making it a valuable component in the development of new chemical processes and products.
Used as a Building Block in Organic Synthesis:
Due to its structural features, C-Thiazol-4-yl-methylamine hydrochloride can act as a building block in organic synthesis, enabling the construction of more complex molecules with potential applications in various industries. Its versatility in forming different chemical entities makes it a valuable asset in the synthesis of specialty chemicals and materials.
It is crucial to handle and store C-Thiazol-4-yl-methylamine hydrochloride with proper safety measures to mitigate any health and environmental risks associated with its use. Adhering to established safety procedures ensures the responsible and effective application of this chemical compound in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 131052-46-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,0,5 and 2 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 131052-46:
(8*1)+(7*3)+(6*1)+(5*0)+(4*5)+(3*2)+(2*4)+(1*6)=75
75 % 10 = 5
So 131052-46-5 is a valid CAS Registry Number.
131052-46-5Relevant articles and documents
Catalytic Staudinger Reduction at Room Temperature
Lenstra, Danny C.,Wolf, Joris J.,Mecinovi?, Jasmin
, p. 6536 - 6545 (2019/05/24)
We report an efficient catalytic Staudinger reduction at room temperature that enables the preparation of a structurally diverse set of amines from azides in excellent yields. The reaction is based on the use of catalytic amounts of triphenylphosphine as a phosphine source and diphenyldisiloxane as a reducing agent. Our catalytic Staudinger reduction exhibits a high chemoselectivity, as exemplified by reduction of azides over other common functionalities, including nitriles, alkenes, alkynes, esters, and ketones.
Quinazoline derivatives possessing anti-tumor activity
-
, (2008/06/13)
The invention relates to quinazoline derivatives, or pharmaceutically-acceptable salts thereof, which possess anti-tumor activity; to processes for their manufacture; and to pharmaceutical compositions containing them. The invention provides a quinazoline of the formula: STR1 wherein R1 is hydrogen or amino, or alkyl or alkoxy each of up to 6 carbon atoms; or R1 is substituted alkyl or alkoxy each of up to 3 carbon atoms; R2 is hydrogen, alkyl, alkenyl, alkynyl, hydroxyalkyl, halogenoalkyl or cyanoalkyl each of up to 6 carbon atoms; Ar is phenylene or heterocyclene; L is a group of the formula --CO.NH--, --NH.CO--, --CO.NR3 --, --NR3. CO--, --CH=CH--, --CH2 O--, --OCH2, --CH2 S--, --SCH2 --, --CO.CH2 --, --CH2.CO-- or --CO.O--, wherein R3 is alkyl of up to 6 carbon atoms; and Y is aryl or heteroaryl or a hydrogenated derivative thereof: or Y is a group of the formula --A--Y1 in which A is alkylene, cycloalkylene, alkenylene or alkynylene each of up to 6 carbon atoms and Y1 is aryl or heteroaryl or a hydrogenated derivative thereof; or a pharmaceutically-acceptable salt thereof.
