131052-47-6

Basic information

• Product Name: 3,5-DIMETHYL-4-ISOXAZOLEMETHANAMINE
• Synonyms: 3,5-DIMETHYL-4-ISOXAZOLEMETHANAMINE;4-AMINOMETHYL-3,5-DIMETHYLISOXAZOLE;3,5-DIMETHYL-4-ISOXAZOLEMETHANAMINE 97.0%;(3,5-dimethylisoxazol-4-yl)methylamine;(3,5-dimethylisoxazol-4-yl)methylamine hydrochloride;1-(3,5-dimethylisoxazol-4-yl)methanamine(SALTDATA: 1.1HCl);(diMethyl-1,2-oxazol-4-yl)MethanaMine;(3,5-Dimethylisoxazol-4-yl)methylamine, 4-(Aminomethyl)-3,5-dimethyl-1,2-oxazole
• CAS NO: 131052-47-6
• Molecular Formula: C₆H₁₀N₂O
• Molecular Weight: 126.1564
• Product Categories: Aminomethyl's;Oxazoles, Isoxazoles & Benzoxazoles;Oxazole&Isoxazole;Oxazoles, Isoxazoles & Benzoxazoles
• Mol File: 131052-47-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 239.9 ºC at 760 mmHg
• Flash Point: 98.9 ºC
• Appearance: /
• Density: 1.069 g/cm3
• Vapor Pressure: 0.0392mmHg at 25°C
• Refractive Index: 1.5
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 8.30±0.29(Predicted)
• CAS DataBase Reference: 3,5-DIMETHYL-4-ISOXAZOLEMETHANAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DIMETHYL-4-ISOXAZOLEMETHANAMINE(131052-47-6)
• EPA Substance Registry System: 3,5-DIMETHYL-4-ISOXAZOLEMETHANAMINE(131052-47-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 131052-47-6(Hazardous Substances Data)

Usage

General Description

3,5-Dimethyl-4-isoxazolemethanamine is a chemical compound with the molecular formula C6H9NO. It is a derivative of isoxazole and is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. 3,5-DIMETHYL-4-ISOXAZOLEMETHANAMINE has demonstrated potential as an anti-inflammatory agent and has been studied for its potential use in the treatment of neurodegenerative diseases. It is also used in the development of new catalysts and ligands for organic synthesis. Additionally, 3,5-Dimethyl-4-isoxazolemethanamine is known for its wide range of biological activities, including antimicrobial, antiparasitic, and antifungal properties, making it a valuable chemical in the field of medicinal chemistry.

InChI:InChI=1/C6H10N2O/c1-4-6(3-7)5(2)9-8-4/h3,7H2,1-2H3

Upstream product

• 19788-37-5 4-chloromethyl-3,5-dimethylisoxazole 

Downstream Products

• 1333995-05-3 C₁₈H₁₉FN₂O₄ 
• 1311749-74-2 C₁₈H₁₉FN₂O₄ 
• 1311698-18-6 C₁₉H₂₂N₂O₄ 
• 1311777-07-7 C₁₉H₂₂N₂O₄ 
• 1311483-54-1 C₁₇H₁₈N₂O₄ 
• 1311909-53-1 C₁₈H₂₀N₂O₄ 
• 1449137-78-3 3,4-dihydro-1H-pyrrolo[2,1-c][1,4]oxazine-6,8-dicarboxylic acid 6-[(3,5-dimethylisoxazol-4-ylmethyl)amide] 8-[((R)-1-phenylpropyl)amide] 
• 1145785-85-8 N-[(3,5-dimethyl-4-isoxazolyl)methyl]-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]-3-pyridazinamine 
• 321435-45-4 (R)-3-((2S,4R)-4-Benzyl-5-oxo-tetrahydro-furan-2-carbonyl)-5,5-dimethyl-thiazolidine-4-carboxylic acid (3,5-dimethyl-isoxazol-4-ylmethyl)-amide 
• 935855-06-4 4-bromo-N-(3,5-dimethyl-isoxazol-4-ylmethyl)-3-fluoro-benzamide 

Relevant articles and documents

SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF

Provided herein are small molecule activators of Nicotinamide Phosphoribosyltransferase (NAMPT), compositions comprising the compounds, and methods of using the compounds and compositions.

Quinazoline derivatives possessing anti-tumor activity

The invention relates to quinazoline derivatives, or pharmaceutically-acceptable salts thereof, which possess anti-tumor activity; to processes for their manufacture; and to pharmaceutical compositions containing them. The invention provides a quinazoline of the formula: STR1 wherein R1 is hydrogen or amino, or alkyl or alkoxy each of up to 6 carbon atoms; or R1 is substituted alkyl or alkoxy each of up to 3 carbon atoms; R2 is hydrogen, alkyl, alkenyl, alkynyl, hydroxyalkyl, halogenoalkyl or cyanoalkyl each of up to 6 carbon atoms; Ar is phenylene or heterocyclene; L is a group of the formula --CO.NH--, --NH.CO--, --CO.NR3 --, --NR3. CO--, --CH=CH--, --CH2 O--, --OCH2, --CH2 S--, --SCH2 --, --CO.CH2 --, --CH2.CO-- or --CO.O--, wherein R3 is alkyl of up to 6 carbon atoms; and Y is aryl or heteroaryl or a hydrogenated derivative thereof: or Y is a group of the formula --A--Y1 in which A is alkylene, cycloalkylene, alkenylene or alkynylene each of up to 6 carbon atoms and Y1 is aryl or heteroaryl or a hydrogenated derivative thereof; or a pharmaceutically-acceptable salt thereof.