131052-82-9

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2(1H)-Pyridinone,4-(aminomethyl)-(9CI) is used as a building block for the synthesis of various pharmaceuticals and agrochemicals. Its unique structure allows for the development of new compounds with potential therapeutic and pesticidal properties.
Used in Dye and Pigment Production:
2(1H)-Pyridinone,4-(aminomethyl)-(9CI) serves as an intermediate in the production of dyes and pigments, contributing to the coloration and stability of these products in various applications.
Used in Material Development:
2(1H)-Pyridinone,4-(aminomethyl)-(9CI) has potential applications in the development of new materials, such as polymers and composites, due to its reactive functional groups and compatibility with other chemical entities.
Used as a Reagent in Organic Chemistry Reactions:
In the realm of organic chemistry, 2(1H)-Pyridinone,4-(aminomethyl)-(9CI) is utilized as a reagent to facilitate various chemical transformations, enabling the synthesis of complex organic molecules and compounds.

Upstream product

• 15871-85-9 6-methoxynicotinonitrile 
• 72716-86-0 4-cyano-2-methoxypyridine 
• 148900-69-0 (2-methoxy-pyridin-4-yl)-methylamine 

Downstream Products

• 943751-74-4 tert-butyl (2-oxo-1,2-dihydro-pyridin-4-ylmethyl)-carbamate 
• 1445732-99-9 N-(2-oxo-1,2-dihydropyridin-4-ylmethyl)-C-phenyl-methanesulfonamide 
• 1445750-91-3 C₁₃H₂₀N₂O₃S 
• 949304-75-0 (2-hydroxyphenyl)[5-(2-hydroxypyridin-4-yl)-1H-pyrrol-3-yl]methanone 
• 131052-83-0 p-[N-(3,4-dihydro-2-methyl-4-oxo-3-pivaloyloxymethylquinazolin-6-ylmethyl)-N-(prop-2-ynyl)amino]-N-(2-hydroxypyrid-4-ylmethyl)benzamide 

Relevant academic research and scientific papers

COMPOSITIONS AND METHODS FOR MODULATING THE WNT SIGNALING PATHWAY

The present invention relates to compositions and methods for modulating the Wnt signaling pathway, using compounds having Formula (1) and (3): wherein A, B, Y and Z all represent rings, and R1, R2, R3 are as defined herein.

Quinazoline derivatives possessing anti-tumor activity

The invention relates to quinazoline derivatives, or pharmaceutically-acceptable salts thereof, which possess anti-tumor activity; to processes for their manufacture; and to pharmaceutical compositions containing them. The invention provides a quinazoline of the formula: STR1 wherein R1 is hydrogen or amino, or alkyl or alkoxy each of up to 6 carbon atoms; or R1 is substituted alkyl or alkoxy each of up to 3 carbon atoms; R2 is hydrogen, alkyl, alkenyl, alkynyl, hydroxyalkyl, halogenoalkyl or cyanoalkyl each of up to 6 carbon atoms; Ar is phenylene or heterocyclene; L is a group of the formula --CO.NH--, --NH.CO--, --CO.NR3 --, --NR3. CO--, --CH=CH--, --CH2 O--, --OCH2, --CH2 S--, --SCH2 --, --CO.CH2 --, --CH2.CO-- or --CO.O--, wherein R3 is alkyl of up to 6 carbon atoms; and Y is aryl or heteroaryl or a hydrogenated derivative thereof: or Y is a group of the formula --A--Y1 in which A is alkylene, cycloalkylene, alkenylene or alkynylene each of up to 6 carbon atoms and Y1 is aryl or heteroaryl or a hydrogenated derivative thereof; or a pharmaceutically-acceptable salt thereof.