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1310579-70-4

C24H16Cl2O3 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1310579-70-4 Structure

  • Basic information

    1. Product Name: C24H16Cl2O3
    2. Synonyms:
    3. CAS NO:1310579-70-4
    4. Molecular Formula:
    5. Molecular Weight: 423.295
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1310579-70-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C24H16Cl2O3(CAS DataBase Reference)
    10. NIST Chemistry Reference: C24H16Cl2O3(1310579-70-4)
    11. EPA Substance Registry System: C24H16Cl2O3(1310579-70-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1310579-70-4(Hazardous Substances Data)

1310579-70-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1310579-70-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,0,5,7 and 9 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1310579-70:
(9*1)+(8*3)+(7*1)+(6*0)+(5*5)+(4*7)+(3*9)+(2*7)+(1*0)=134
134 % 10 = 4
So 1310579-70-4 is a valid CAS Registry Number.

1310579-70-4Downstream Products

1310579-70-4Relevant articles and documents

The identification of 4,7-disubstituted naphthoic acid derivatives as UDP-competitive antagonists of P2Y14

Gauthier, Jacques Yves,Belley, Michel,Deschênes, Denis,Fournier, Jean-Fran?ois,Gagné, Sébastien,Gareau, Yves,Hamel, Martine,Hénault, Martin,Hyjazie, Huda,Kargman, Stacia,Lavallée, Geneviève,Levesque, Jean-Fran?ois,Li, Lianhai,Mamane, Ya?l,Mancini, Joseph,Morin, Nicolas,Mulrooney, Erin,Robichaud, Jo?l,Thérien, Michel,Tranmer, Geoffrey,Wang, Zhaoyin,Wu, Jin,Black, W. Cameron

scheme or table, p. 2836 - 2839 (2011/06/24)

A weak, UDP-competitive antagonist of the pyrimidinergic receptor P2RY 14 with a naphthoic acid core was identified through high-throughput screening. Optimization provided compounds with improved potency but poor pharmacokinetics. Acylglucuronidation was determined to be the major route of metabolism. Increasing the electron-withdrawing nature of the substituents markedly reduced glucuronidation and improved the pharmacokinetic profile. Additional optimization led to the identification of compound 38 which is an 8 nM UDP-competitive antagonist of P2Y14 with a good pharmacokinetic profile.

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