1310584-14-5 Usage
Reaction
Palladium precatalyst for Suzuki-Miyaura coupling reactions.
Uses
Different sources of media describe the Uses of 1310584-14-5 differently. You can refer to the following data:
1. XPhos Pd G2 is a used as a catalyst in chemical reactions.
2. XPhos Pd G2 was employed as catalyst in the following reactions:Palladium-catalyzed Suzuki-Miyaura coupling reactions of potassium organotrifluoroborates and sulfamates. Suzuki-Miyaura cross-coupling reactions of sensitive aryl and heteroarylboronic acids.Synthesis of potassium Boc-protected secondary aminomethyltrifluoroborates, via Suzuki-Miyaura cross-coupling reaction.
General Description
XPhos Pd G2 is a bulky monodentate biaryl ligand. It is a Buchwald′s 2nd generation preformed catalyst. It undergoes rapid reductive elimination to form a reactive, monoligated Pd(0) species.
Check Digit Verification of cas no
The CAS Registry Mumber 1310584-14-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,0,5,8 and 4 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1310584-14:
(9*1)+(8*3)+(7*1)+(6*0)+(5*5)+(4*8)+(3*4)+(2*1)+(1*4)=115
115 % 10 = 5
So 1310584-14-5 is a valid CAS Registry Number.
1310584-14-5Relevant articles and documents
A new palladium precatalyst allows for the fast Suzuki-Miyaura coupling reactions of unstable polyfluorophenyl and 2-heteroaryl boronic acids
Kinzel, Tom,Zhang, Yong,Buchwald, Stephen L.
, p. 14073 - 14075 (2011/01/04)
Boronic acids which quickly deboronate under basic conditions, such as polyfluorophenylboronic acid and five-membered 2-heteroaromatic boronic acids, are especially challenging coupling partners for Suzuki-Miyaura reactions. Nevertheless, being able to use these substrates is highly desirable for a number of applications. Having found that monodentate biarylphosphine ligands can promote these coupling processes, we developed a precatalyst that forms the catalytically active species under conditions where boronic acid decomposition is slow. With this precatalyst, Suzuki-Miyaura reactions of a wide range of (hetero)aryl chlorides, bromides, and triflates with polyfluorophenyl, 2-furan, 2-thiophene, and 2-pyrroleboronic acids and their analogues proceed at room temperature or 40 °C in short reaction times to give the desired products in excellent yields.