131066-05-2Relevant academic research and scientific papers
Reaction of Dialkyl Phosphites with α-Enones, II. - 2:1 Adducts from Dimethyl Phosphite and α-Enones: Synthesis of (1-Hydroxy-1,3-alkanediyl)diphosphonates and 5-Dimethoxyphosphoryl-2-methoxy-1,2-oxaphospholane P-Oxides
Oehler, Elisabeth,Zbiral, Erich
, p. 229 - 236 (2007/10/02)
On NaOCH3-catalyzed reaction with two equivalents of dimethyl phosphite (2), various α-enones 1 are transformed into the diphosphonates 5 (e.g. 5a, 5b, 5e, 5f), which, depending on the structure of the enone, can further react with ring closure to give th
Reaction of Dialkyl Phosphites with α-Enones. I. - Synthesis and Allylic Rearrangement of Dimethyl (1-Hydroxy-2-alkenyl)- and (1-Hydroxy-2-cycloalkenyl)phosphonates
Oehler, Elisabeth,Zbiral, Erich
, p. 175 - 184 (2007/10/02)
Various β,γ-unsaturated α-hydroxyphosphonates 3 are prepared in good yields by NaOCH3-catalyzed regioselective 1,2-addition of dimethyl phosphite to acyclic and cyclic α-enones at -35 deg C.On acid-catalyzed acetylation, the allylic α-hydroxyphosphonates
