1310680-43-3 Usage
General Description
(S)-Boc-3-amino-4,4,4-trifluoro-butyric acid, also known as (S)-Boc-AF3B, is a chemical compound that belongs to the family of amino acids. It is a derivative of the naturally occurring amino acid, alanine. The term "Boc" in its name stands for tert-butoxycarbonyl, which is a protective group commonly used in organic synthesis to protect the amine group. The trifluoro-butyric acid moiety in the compound contains a trifluoromethyl group, which is often used to enhance the metabolic stability and lipophilicity of drug molecules. (S)-Boc-3-amino-4,4,4-trifluoro-butyric acid is commonly used as a building block in the synthesis of pharmaceutical compounds and can also be used as a precursor for the preparation of fluorine-labeled compounds for PET imaging.
Check Digit Verification of cas no
The CAS Registry Mumber 1310680-43-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,0,6,8 and 0 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1310680-43:
(9*1)+(8*3)+(7*1)+(6*0)+(5*6)+(4*8)+(3*0)+(2*4)+(1*3)=113
113 % 10 = 3
So 1310680-43-3 is a valid CAS Registry Number.
1310680-43-3Relevant articles and documents
Stereo-regulated synthesis of peptides containing a β-trifluoromethyl- β-amino acid
Cho, Joon-Il,Nishizono, Nao,Iwahashi, Nobutaka,Saigo, Kazuhiko,Ishida, Yasuhiro
, p. 9252 - 9260 (2013/10/01)
For the chemical conversions of a β-trifluoromethyl-β-amino acid ((S)-4,4,4-trifluoro-3-aminobutyric acid, 1), such as the N-terminus protection with benzyloxycarbonyl or tert-butoxycarbonyl group, the C-terminus protection with benzyl or tert-butyl group, and peptide elongation at the both termini, highly practical protocols were established. Through these conversions, the stereochemistry of 1 and/or its condensation counterpart was maintained. Because the protocols developed here are indispensable for the application of 1 in peptide engineering, they would expand the utility of 1 and its derivatives.
SUBSTITUTED SULFONAMIDOPROPIONAMIDES AND METHODS OF USE
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Page/Page column 126, (2010/10/20)
This invention is in the field of pharmaceutical agents and specifically relates to compounds, compositions, uses and methods for treating inflammation-related disorders, including pain.
