1310681-36-7Relevant articles and documents
Novel N-chloroheterocyclic antimicrobials
Francavilla, Charles,Turtle, Eric D.,Kim, Bum,O'Mahony, Donogh J.R.,Shiau, Timothy P.,Low, Eddy,Alvarez, Nichole J.,Celeri, Chris E.,D'Lima, Louisa,Friedman, Lisa C.,Ruado, Francis S.,Xu, Ping,Zuck, Meghan E.,Anderson, Mark B.,Najafi, Ramin,Jain, Rakesh K.
, p. 3029 - 3033 (2011)
Antimicrobial compounds with broad-spectrum activity and minimal potential for antibiotic resistance are urgently needed. Toward this end, we prepared and investigated a novel series of N-chloroheterocycles. Of the compounds examined, the N-chloroamine series were found superior over N-chloroamide series in regards to exhibiting high antimicrobial activity, low cytotoxicity, and long-term aqueous stability.
