1310686-23-7 Usage
Description
1-isothiocyanato-PEG3-Azide is a versatile chemical compound that features a polyethylene glycol (PEG) backbone with three ethylene glycol units, an isothiocyanate functional group, and an azide functional group. The PEG backbone endows the compound with water solubility and biocompatibility, which are advantageous for a range of biological and biomedical applications. The isothiocyanate group facilitates reactions with amine-containing molecules, while the azide group is reactive in copper-catalyzed or copper-free azide-alkyne cycloaddition reactions, enabling the compound to be attached to other molecules or surfaces. These features make 1-isothiocyanato-PEG3-Azide a valuable tool in biomedical research, drug delivery, and diagnostics.
Uses
Used in Biomedical Research:
1-isothiocyanato-PEG3-Azide is used as a bioconjugation agent for attaching biologically active molecules to various surfaces or other molecules, leveraging its isothiocyanate and azide functional groups to facilitate stable and specific linkages.
Used in Drug Delivery Systems:
1-isothiocyanato-PEG3-Azide is used as a component in the design of drug delivery systems, enhancing the solubility, stability, and targeting of therapeutic agents. Its PEG backbone and reactive functional groups allow for the modification and functionalization of drug carriers to improve their performance in vivo.
Used in Diagnostics:
1-isothiocyanato-PEG3-Azide is used as a labeling agent for the development of diagnostic tools, such as imaging probes and biosensors. Its ability to covalently attach to biomolecules and its compatibility with various detection techniques make it suitable for enhancing the sensitivity and specificity of diagnostic assays.
Used in Material Science:
1-isothiocyanato-PEG3-Azide is used as a functionalizing agent for the modification of surfaces and materials, improving their biocompatibility, resistance to protein adsorption, and other properties relevant to medical devices and biomaterials.
Used in Chemical Synthesis:
1-isothiocyanato-PEG3-Azide is used as an intermediate in the synthesis of more complex molecules, taking advantage of its reactive functional groups to build molecular structures with specific properties and functions for various applications in the chemical and pharmaceutical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 1310686-23-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,0,6,8 and 6 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1310686-23:
(9*1)+(8*3)+(7*1)+(6*0)+(5*6)+(4*8)+(3*6)+(2*2)+(1*3)=127
127 % 10 = 7
So 1310686-23-7 is a valid CAS Registry Number.
1310686-23-7Relevant articles and documents
Bicyclic (galacto)nojirimycin analogues as glycosidase inhibitors: Effect of structural modifications in their pharmacological chaperone potential towards β-glucocerebrosidase
Aguilar-Moncayo, Matilde,Garcia-Moreno, M. Isabel,Trapero, Ana,Egido-Gabas, Meritxell,Llebaria, Amadeu,Garcia Fernandez, Jose M.,Ortiz Mellet, Carmen
supporting information; experimental part, p. 3698 - 3713 (2011/06/20)
A molecular-diversity-oriented approach for the preparation of bicyclic sp2-iminosugar glycomimetics related to nojirimycin and galactonojirimycin is reported. The synthetic strategy takes advantage of the ability of endocyclic pseudoamide-type
