1310697-89-2 Usage
Description
(3-bromo-5-fluoro-phenoxy)-tert-butyl-dimethyl-silane is a chemical compound with the molecular formula C16H22BrFOSi. It is a silane derivative that features a bromine atom, a fluorine atom, a phenoxy group, and tert-butyl and dimethyl substituents. (3-bromo-5-fluoro-phenoxy)-tert-butyl-dimethyl-silane is known for its unique chemical structure and properties, which make it a valuable tool in various scientific and industrial applications.
Uses
Used in Organic Synthesis:
(3-bromo-5-fluoro-phenoxy)-tert-butyl-dimethyl-silane is used as a reagent in the field of organic synthesis, particularly for the construction of silicon-containing compounds. Its presence in the synthesis process aids in the formation of complex molecular structures that are otherwise challenging to achieve.
Used in Materials Science:
In the field of materials science, (3-bromo-5-fluoro-phenoxy)-tert-butyl-dimethyl-silane is utilized for the development of functional coatings and advanced materials. Its unique properties contribute to the enhancement of material characteristics, such as durability, stability, and performance in specific applications.
Used in Research and Development:
Due to its distinctive chemical structure, (3-bromo-5-fluoro-phenoxy)-tert-butyl-dimethyl-silane serves as a valuable tool for research and development across different scientific and industrial fields. It can be employed to study various chemical reactions and to develop new methodologies and applications in chemistry and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 1310697-89-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,0,6,9 and 7 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1310697-89:
(9*1)+(8*3)+(7*1)+(6*0)+(5*6)+(4*9)+(3*7)+(2*8)+(1*9)=152
152 % 10 = 2
So 1310697-89-2 is a valid CAS Registry Number.
1310697-89-2Relevant articles and documents
Facile synthesis of 1,2-dione-containing abietane analogues for the generation of human carboxylesterase inhibitors
Binder, Randall J.,Hatfield, M. Jason,Chi, Liying,Potter, Philip M.
supporting information, p. 79 - 89 (2018/03/06)
Recently, a series of selective human carboxylesterase inhibitors have been identified based upon the tanshinones, with biologically active molecules containing a 1,2-dione group as part of a naphthoquinone core. Unfortunately, the synthesis of such compounds is complex. Here we describe a novel method for the generation of 1,2-dione containing diterpenoids using a unified approach, by which boronic acids are joined to vinyl bromo-cyclohexene derivatives via Suzuki coupling, followed by electrocyclization and oxidation to the o-phenanthroquinones. This has allowed the construction of a panel of miltirone analogues containing an array of substituents (methyl, isopropyl, fluorine, methoxy) which have been used to develop preliminary SAR with the two human carboxylesterase isoforms. As a consequence, we have synthesized highly potent inhibitors of these enzymes (Ki 15 nM), that maintain the core tanshinone scaffold. Hence, we have developed a facile and reproducible method for the synthesis of abietane analogues that have resulted in a panel of miltirone derivatives that will be useful tool compounds to assess carboxylesterase biology.
ANALGESIC COMPOUNDS, METHODS, AND FORMULATIONS
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Paragraph 0050, (2013/09/12)
Provided are analgesic compounds, and salts thereof, of formula: (I) wherein A is: (A) Additionally, pharmaceutical formulations and methods of use employing the above compounds are provided.
ANALGESIC COMPOUNDS, METHODS, AND FORMULATIONS
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Page/Page column 16, (2012/08/08)
Provided are analgesic compounds, and salts thereof, of formula: ( I ) wherein A is: ( A ) Additionally, pharmaceutical formulations and methods of use employing the above compounds are provided.
