13107-20-5Relevant academic research and scientific papers
Synthetic method of 4-bromine spiro[fluorine-9,9'-xanthene]
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Paragraph 0009; 0010; 0011; 0012; 0013; 0014; 0015, (2017/08/29)
The invention discloses a synthetic method of 4-bromine spiro[fluorine-9,9'-xanthene] and belongs to the field of organic synthesis. The synthetic method is realized by the following steps: taking diphenyl ether as a raw material, and enabling the dipheny
Renin Inhibitors
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Page/Page column 50, (2010/12/29)
Disclosed are compounds having the formula (I): wherein the R1, R2, R3, X, Y, A, L, and G are defined herein. These compounds bind to aspartic proteases to inhibit their activity and are useful in the treatment or amelioration of diseases associated with aspartic protease activity. Also disclosed are methods of use of the compounds of Formula I for ameliorating or treating aspartic protease related disorders in a subject in need thereof.
RENIN INHIBITORS
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Page/Page column 72, (2008/12/04)
Disclosed are compounds of Formula I, wherein the R, R1, R2, R3, X, Y, A, Q, E, and G are defined herein. These compounds bind to aspartic proteases to inhibit their activity and are useful in the treatment or amelioration
The search for tolerant Lewis acid catalysts. Part 2: Enantiopure cycloalkyldialkylsilyl triflimide catalysts
Tang, Zilong,Mathieu, Benoit,Tinant, Bernard,Dive, Georges,Ghosez, Léon
, p. 8449 - 8462 (2008/02/09)
A series of 2-aryl- and arylmethyl-3-dialkylphenylsilyl cycloalkanones have been prepared and resolved. The pure enantiomers were reduced to the corresponding cycloalkane derivatives. These were used for the in situ generation of enantiopure cycloalkylsil
PIPERIDINE AND MORPHOLINE RENIN INHIBITORS
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Page/Page column 171, (2008/06/13)
Described are compounds which are orally active and bind to renin to inhibit its activity. They are useful in the treatment or amelioration of diseases associated with renin activity. Also described are methods of use of these compounds for treating or ameliorating a renin mediated disorder in a subject.
REAKTIONSWAERMEN ISOMERER (LITHIOARYL)ETHER MIT s-BUOH
Klumpp, G. W.,Sinnige, M. J.
, p. 2247 - 2250 (2007/10/02)
The enthalpies of (2-lithioaryl) ethers and that of 8-lithio-1-methoxynaphthyllithium in di-n-butyl ether are lower than those of their 4-lithio isomers by ca. 20 and 28 kJ/(mol RLi), respectively.
