131074-55-0

Basic information

• Product Name: (S)-(+)-1-(1-NAPHTHYL)ETHYL ISOTHIOCYANATE
• Synonyms: (S)-(+)-1-(1-NAPHTHYL)ETHYL ISOTHIOCYANATE;1-[(1S)-1-isothiocyanatoethyl]-Naphthalene
• CAS NO: 131074-55-0
• Molecular Formula: C₁₃H₁₁NS
• Molecular Weight: 213.3
• EINECS: -0
• Mol File: 131074-55-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 354.4°C at 760 mmHg
• Flash Point: 177.8°C
• Appearance: /
• Density: 1,154 g/cm3
• Vapor Pressure: 6.85E-05mmHg at 25°C
• Refractive Index: 1.6540
• Sensitive: Moisture Sensitive
• BRN: 8682202
• CAS DataBase Reference: (S)-(+)-1-(1-NAPHTHYL)ETHYL ISOTHIOCYANATE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(+)-1-(1-NAPHTHYL)ETHYL ISOTHIOCYANATE(131074-55-0)
• EPA Substance Registry System: (S)-(+)-1-(1-NAPHTHYL)ETHYL ISOTHIOCYANATE(131074-55-0)

Safety Data

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: 2810
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 131074-55-0(Hazardous Substances Data)

Usage

General Description

(S)-(+)-1-(1-Naphthyl)ethyl isothiocyanate is a chemical compound that is commonly used in organic synthesis. It is a member of the isothiocyanate family, which are known for their distinct odor and potential health benefits. This particular compound is often used as a reagent in chemical reactions, particularly in the synthesis of various organic compounds. It is also used in research and pharmaceutical development due to its potential medicinal properties. Additionally, it has been studied for its potential as an antioxidant and anti-inflammatory agent. Overall, (S)-(+)-1-(1-Naphthyl)ethyl isothiocyanate is a versatile compound with a wide range of applications in the field of chemistry and biochemistry.

InChI:InChI=1/C13H11NS/c1-10(14-9-15)12-8-4-6-11-5-2-3-7-13(11)12/h2-8,10H,1H3/t10-/m0/s1

Upstream product

• 463-71-8 thiophosgene 
• 10420-89-0 (S)-1-(1-Naphthyl)ethylamine 

Downstream Products

• 1215176-32-1 C₃₅H₄₁N₃S 
• 313695-95-3 (4S,5S)-4,5-diphenyl-1-ethoxycarbonyl-2-[(S)-1-(1-naphthyl)ethylimino]imidazolidine 
• 313695-89-5 N-[(1S,2S)-1,2-diphenyl-2-ethoxycarbonylaminoethyl]-N'-[(S)-1-(1-naphthyl)ethyl]thiourea 

Relevant articles and documents

Crystallographic, 1H NMR and CD studies of sterically strained thiourea anion receptors possessing two stereogenic centres

The synthesis and structural characterisation of three chiral bis-naphthalene thiourea receptors (1-3) derived from (R)-(+)-1-(1-naphthyl) ethylamine and (S)-(-)-1-(1-naphthyl)ethylamine are reported along with spectroscopic studies to screen their potential as anion receptors/sensors. Their solid state structures were analysed by X-ray crystallography and their ability to bind anions such as acetate and phosphate in DMSO solution investigated by 1H NMR, absorption, fluorescence and circular dichroism spectroscopy.

Modified guanidines as potential chiral superbases. 2. Preparation of 1,3-unsubstituted and 1-substituted 2-iminoimidazolidine derivatives and a related guanidine by the 2-chloro-1,3-dimethylimidazolinium chloride-induced cyclization of thioureas

Simple preparation methods for modified guanidines were explored for new chiral superbases. Thus, (4S,5S)-4,5-diphenyl- and diastereomeric cyclohexane-fused 2-iminoimidazolidines were prepared from (1S,2S) - 1,2 -diphenylethylenediamine and (1R,2R)- or (1S,2S)-1,2-diaminocyclohexanes through cyclization of protected thiourea intermediates with 2-chloro-1,3-dimethylimidazolinium chloride (DMC) as a key reaction. In the (4S,5S)-4,5-diphenyl series 1-methyl-2-iminoimidazolidines and 2-diethylaminoimidazoline were also prepared as related guanidines.