131084-55-4

Basic information

• Product Name: 5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE
• Synonyms: 5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE;5-Chloro-6-azaindole;1H-Pyrrolo[2,3-c]pyridine, 5-chloro-;1H-PYRROLO[3,2-C]PYRIDIN,5-CHLORO-
• CAS NO: 131084-55-4
• Molecular Formula: C₇H₅ClN₂
• Molecular Weight: 152.58
• Product Categories: Heterocycle-Pyridine series
• Mol File: 131084-55-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 335.8 °C at 760 mmHg
• Flash Point: 187.2 °C
• Appearance: /
• Density: 1.425
• Vapor Pressure: 0.000228mmHg at 25°C
• Refractive Index: 1.703
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 13.75±0.40(Predicted)
• CAS DataBase Reference: 5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE(131084-55-4)
• EPA Substance Registry System: 5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE(131084-55-4)

Safety Data

• Hazardous Substances Data: 131084-55-4(Hazardous Substances Data)

Usage

General Description

5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE is a chemical compound with the molecular formula C9H5ClN2. It is a heterocyclic compound containing a pyrrole ring fused to a pyridine ring with a chlorine atom at the 5-position. 5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE has potential applications in pharmaceuticals, agrochemicals, and materials science. It is commonly used as an intermediate in the synthesis of various organic compounds and can also act as a building block in the development of new drugs and agrochemicals. The 5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE has been the subject of research and development due to its unique structure and potential pharmacological properties.

InChI:InChI=1/C7H5ClN2/c8-7-3-5-1-2-9-6(5)4-10-7/h1-4,9H

Upstream product

• 23056-33-9 2-chloro-4-methyl-5-nitro-pyridine 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 1214241-85-6 (E)-2-(2-chloro-5-nitropyridin-4-yl)-N,N-dimethylethenamine 
• 142078-36-2 2-(2-chloro-3-nitro-4-pyridyl)-N,N-dimethylethenamineine 

Downstream Products

• 1204501-41-6 5-chloro-1-(benzenesulfonyl)-1H-pyrrolo[2,3-c]pyridine 
• 1221153-79-2 5-chloro-1-isopropyl-1H-pyrrolo[2,3-c]pyridine 

Relevant articles and documents

Heterocyclic compound as FGFR inhibitor, synthesis method and applications thereof

The present invention discloses a heterocyclic compound as an FGFR inhibitor, and a synthesis method thereof, and applications of the heterocyclic compound in preparation of drugs for treating cancers. According to the present invention, the heterocyclic compound as the FGFR inhibitor or the pharmaceutically acceptable salt thereof has high FGFR inhibitory action, and the pharmaceutical composition prepared from the heterocyclic compound has good anticancer effect and wide application range.

New bicyclic compounds as crac channel modulators

The present invention relates to novel compounds which are inhibitors of CRAC channel activity. This invention also relates to pharmaceutical compositions containing them, process for their preparation and their use in therapy.

NOVEL 6-AZAINDOLE AMINOPYRIMIDINE DERIVATIVES HAVING NIK INHIBITORY ACTIVITY

The present invention relates to a compound of formula I: wherein: R1 is C1-6 alkyl, C3-8 cycloalkyl, aryl, heterocyclyl, or -COR1x, where the C1-6 alkyl, C3-8 cycloalkyl, aryl, and heterocyclyl may be substituted; and R1x is C3-8 cycloalkyl, aryl, or heterocyclyl, any of which may be substituted; R2, R3, R4, R5, R6, and R7 are each independently hydrogen, halogen, C1-6 alkyl, or aryl, where the C1-6 alkyl or aryl may be substituted; R8 is hydrogen, C1-6 alkyl, aryl, or heterocyclyl, any of which may be substituted; or a pharmaceutically acceptable salt or ester thereof.