131086-91-4

Basic information

• Product Name: 3,7-dimethoxy-6H-benzo[c]chromen-6-one
• Synonyms: 6H-Dibenzo(b,d)pyran-6-one, 3,7-dimethoxy-
• CAS NO: 131086-91-4
• Molecular Formula: C₁₅H₁₂O₄
• Molecular Weight: 256.2534
• Mol File: 131086-91-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 447.6°C at 760 mmHg
• Flash Point: 201.9°C
• Density: 1.27g/cm³
• Vapor Pressure: 3.31E-08mmHg at 25°C
• Refractive Index: 1.599
• CAS DataBase Reference: 3,7-dimethoxy-6H-benzo[c]chromen-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3,7-dimethoxy-6H-benzo[c]chromen-6-one(131086-91-4)
• EPA Substance Registry System: 3,7-dimethoxy-6H-benzo[c]chromen-6-one(131086-91-4)

Safety Data

• Hazardous Substances Data: 131086-91-4(Hazardous Substances Data)

Upstream product

• 133730-22-0 3-methoxy-2-(N,N-diethylcarboxamido)phenylboronic acid 
• 133730-24-2 1-Bromo-4-methoxy-2-(methoxymethoxy)benzene 
• 63604-94-4 2-bromo-5-methoxyphenol 
• 156050-76-9 3,2',4'-trimethoxy-2-biphenylcarboxylate 
• 133730-28-6 N,N-Diethyl-2'-(methoxymethoxy)-3,4'-dimethoxy-2-biphenylcarboxamide 
• 156050-74-7 methyl-3,2',4'-trimethoxy-2-biphenylcarboxylate 

Downstream Products

• 156050-73-6 benzyl-2'-benzyloxy-3,4'-dimethoxy-2-biphenylcarboxylate 

Relevant articles and documents

Ortho and remote metalation - cross coupling strategies. Total synthesis of the naturally occurring fluorenone dengibsinin and the azafluoranthene alkaloid imeluteine

The total synthesis of the naturally occurring fluorenone, dengibsinin (7a), and the azafluoranthene alkaloid, imeluteine (30e), is described. Using combined ortho metalation - cross coupling sequences that terminate in Friedel-Crafts (18b→6d) and remote

Sequential Directed Ortho Metalation-Boronic Acid Cross-Coupling Reactions. A General Regiospecific Route to Oxygenated Dibenzopyran-6-ones Related to Ellagic Acid

A general regiospecific synthesis of dibenzopyran-6-one derivatives 1a,c and 8a-i related to ellagic acid is described (Scheme I, Table I).The sequence involves directed ortho metalation-boronation of benzamides 4 to give the arylboronic acids 5, which, upon palladium-catalyzed cross-coupling with alkoxybromobenzenes 6 leads to the biphenylamides 7.BBr3 demethylation followed by acid-catalyzed cyclization affords pyranone 8.In this manner, the naturally occurring dibenzopyranones 1a, autumnariol (1c), and the heterocyclic analogue 13 (Scheme III) were efficiently prepared.