1310876-30-2

Upstream product

• 18440-58-9 1-(N-phenylhydrazono)-1-chloropropanone 
• 3382-18-1 6,7-dimethoxy-3,4-dihydro-isoquinoline 
• 1310876-26-6 (E)-1-(8,9-dimethoxy-1-phenyl-1,5,6,10b-tetrahydro-[1,2,4]triazolo[3,4-a]isoquinolin-3-yl)-3-(dimethylamino)-prop-2-en-1-one 
• 132815-80-6 1-chloro-1-(p-tolylhydrazone)propanone 

Downstream Products

• 1310876-39-1 8,9-dimethoxy-3-(7-methyl-2-(4-methylphenyl)-2H-pyrazolo[3,4-d]pyridazin-4-yl)-1-phenyl-1,5,6,10b-tetrahydro-[1,2,4]triazolo[3,4-a]isoquinoline 

Relevant academic research and scientific papers

Synthesis, reactions and antibacterial activity of 3-acetyl[1,2,4] triazolo[3,4-a]isoquinoline derivatives using chitosan as heterogeneous catalyst under microwave irradiation

3-Acetyl[1,2,4]triazolo[3,4-a]isoquinolines were prepared using chitosan as a catalyst. These compounds were used to prepare a novel series of enaminones 5, and their reactions with hydrazonoyl halides 1 and 11 gave triazoloisoquinolines 8 and 13, respectively, with a carbonylpyrazole side chain. Hydrazinolysis of 8 and 13 gave the pyrazolopyridazines 10 and pyrazolopyridazinones 14. Reaction of 5 with hydroximoyl halides 15 led to triazoloisoquinoline 16 with a carbonylisoxazole side chain. Antibacterial effects of compounds 8 and 10 were studied.