1311149-74-2Relevant academic research and scientific papers
[2+2+2] Cycloadditions of alkynylynamides - A total synthesis of perlolyrine and the first total synthesis of "isoperlolyrine"
Dassonneville, Benjamin,Witulski, Bernhard,Detert, Heiner
experimental part, p. 2836 - 2844 (2011/06/23)
The total syntheses of the carboline alkaloids perlolyrine and "isoperlolyrine" are reported. Key-steps of the syntheses are Negishi coupling reactions on alkynylynamides and their metal-catalyzed [2+2+2] cycloadditions with nitriles to form the β- and γ-
