131121-05-6

Basic information

• Product Name: 3-{(5Z,10Z,14Z,19Z)-8-Hydroxy-18-(2-methoxycarbonyl-ethyl)-3,8,13,17-tetramethyl-7-[2-(toluene-4-sulfonyloxy)-eth-(Z)-ylidene]-7,8,21,23-tetrahydro-porphin-2-yl}-propionic acid methyl ester
• CAS NO: 131121-05-6
• Molecular Weight: 752.888
• Mol File: 131121-05-6.mol

Chemical Properties

• CAS DataBase Reference: 3-{(5Z,10Z,14Z,19Z)-8-Hydroxy-18-(2-methoxycarbonyl-ethyl)-3,8,13,17-tetramethyl-7-[2-(toluene-4-sulfonyloxy)-eth-(Z)-ylidene]-7,8,21,23-tetrahydro-porphin-2-yl}-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-{(5Z,10Z,14Z,19Z)-8-Hydroxy-18-(2-methoxycarbonyl-ethyl)-3,8,13,17-tetramethyl-7-[2-(toluene-4-sulfonyloxy)-eth-(Z)-ylidene]-7,8,21,23-tetrahydro-porphin-2-yl}-propionic acid methyl ester(131121-05-6)
• EPA Substance Registry System: 3-{(5Z,10Z,14Z,19Z)-8-Hydroxy-18-(2-methoxycarbonyl-ethyl)-3,8,13,17-tetramethyl-7-[2-(toluene-4-sulfonyloxy)-eth-(Z)-ylidene]-7,8,21,23-tetrahydro-porphin-2-yl}-propionic acid methyl ester(131121-05-6)

Safety Data

• Hazardous Substances Data: 131121-05-6(Hazardous Substances Data)

Upstream product

• 131121-04-5 photopemptoporphyrin alcohol dimethyl ester 
• 98-59-9 p-toluenesulfonyl chloride 
• 17467-73-1 4-vinyldeuteroporphyrin-IX dimethyl ester 
• 131121-03-4 photopemptoporphyrin-IX dimethyl ester 

Relevant articles and documents

Syntheses of oxygen analogues of sulfhemes-A and -C

Syntheses of metal-free oxygen analogues of the sulfhemes-A and -C from protoporphyrin-IX dimethyl ester I are presented. Oxasulfporphyrin-C dimethyl ester 5 is obtained by intramolecular displacement of a primary tosylate by a tertiary hydroxyl in an appropriately constructed precursor 18, or by surface-catalyzed rearrangement of the epoxide-bearing oxasulfporphyrin-A dimethyl ester 23. Compound 23 is in turn prepared by Mitsunobu type internal dehydration of the precursor 12. The methodology is then successfully extended to more symmetric porphyrin systems. Compounds 23, 25, 46, and 61/62 are the first porphyrin epoxides to be synthesized.

Synthesis of oxygen analogues of the sulfchlorins

The oxygen analogues of sulfchlorin-A and-C were synthesized from protoporphyrin-IX dimethyl ester. The developed methodology employs a modified Mitsunobu reaction and produces the first porphyrin epoxides and porphyrinones derived from protoporphyrin-IX.