1311254-86-0 Usage
General Description
(3S)-1H-1,4-Diazepine-1-carboxylic acid, hexahydro-3-Methyl-, phenylMethyl ester is an organic compound commonly used in chemical research and pharmaceutical synthesis. It is an ester derivative of the diazepine carboxylic acid, and its molecular structure includes a six-membered ring containing nitrogen and a phenyl group. (3S)-1H-1,4-Diazepine-1-carboxylic acid, hexahydro-3-Methyl-, phenylMethyl ester has potential pharmacological properties due to its diazepine structure, and it may be used in the development of new drugs targeting the central nervous system or other biological processes. Its specific properties and potential applications should be further investigated through detailed research and testing.
Check Digit Verification of cas no
The CAS Registry Mumber 1311254-86-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,1,2,5 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1311254-86:
(9*1)+(8*3)+(7*1)+(6*1)+(5*2)+(4*5)+(3*4)+(2*8)+(1*6)=110
110 % 10 = 0
So 1311254-86-0 is a valid CAS Registry Number.
1311254-86-0Relevant articles and documents
A practical synthesis of (S)- tert -butyl 3-methyl-1,4-diazepane-1- carboxylate, the key intermediate of rho-kinase inhibitor K-115
Gomi, Noriaki,Kouketsu, Akiyasu,Ohgiya, Tadaaki,Shibuya, Kimiyuki
, p. 3171 - 3178 (2012/11/14)
A practical synthesis of (S)-tert-butyl 3-methyl-1,4-diazepane-1- carboxylate has been established for supplying this key intermediate of Rho-kinase inhibitor K-115 in a multikilogram production. The chiral 1,4-diazepane was constructed by intramolecular Fukuyama-Mitsunobu cyclization of a N-nosyl diamino alcohol starting from the commercially available (S)- or (R)-2-aminopropan-1-ol. In the same manner, an enantiomeric pair of a structural isomer were prepared for demonstration of the synthetic utility.
