1311274-06-2

Basic information

• Product Name: C₅₆H₇₈N₁₀O₁₂
• CAS NO: 1311274-06-2
• Molecular Weight: 1083.3
• Mol File: 1311274-06-2.mol

Chemical Properties

• CAS DataBase Reference: C₅₆H₇₈N₁₀O₁₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₆H₇₈N₁₀O₁₂(1311274-06-2)
• EPA Substance Registry System: C₅₆H₇₈N₁₀O₁₂(1311274-06-2)

Safety Data

• Hazardous Substances Data: 1311274-06-2(Hazardous Substances Data)

Upstream product

• 53293-00-8 hex-5-ynoic acid 
• 29022-11-5 N-(fluoren-9-ylmethoxycarbonyl)glycine 
• 35661-60-0 Fmoc-Leu-OH 
• 35661-40-6 N-Fmoc L-Phe 
• 75932-02-4 N-2,N-6-bis(9-fluorenylmethyloxycarbonyl)-L-lysine 

Relevant articles and documents

Synthesis and characterization of enzymatically degradable PEG-based peptide-containing hydrogels

Biodegradable hydrogels were synthesized by the click reaction of 4-arm azido-terminated PEG differing in molecular weight (2 100 and 8 800) and two alkyne-terminated peptides: [alkyne]-GFLGK-[alkyne] and ([alkyne]-GFLG) 2K. The physical properties of in situ formed hydrogels were examined. The hydrogels were highly elastic as determined by rheological and microrheological studies. Swelling degree and enzymatic degradation by papain were dependent on the molecular weight of the PEG, but not the peptide. For PEG8800-based hydrogels, timecourse analysis of degradation showed that the molecular weight of the soluble fraction quickly reached the PEG precursor value. These findings may guide future design of hydrogels with controllable mechanical properties and enzymatic degradability. (Figure Presented)