1311292-01-9Relevant academic research and scientific papers
Modular assembly of macrocyclic organo-peptide hybrids using synthetic and genetically encoded precursors
Smith, Jessica M.,Vitali, Francesca,Archer, Steven A.,Fasan, Rudi
, p. 5075 - 5080 (2011/06/28)
Mix, click, cyclize: Conformationally constrained organo-peptide hybrids can be constructed by a tandem chemoselective reaction between a synthetic molecule and a recombinant protein. Diverse macrocyclic structures were obtained in cyclic, lariat, and protein-tethered configurations by varying the nature of the synthetic and biosynthetic precursors. Copyright
