13113-70-7

Upstream product

• 591-50-4 iodobenzene 
• 201230-82-2 carbon monoxide 
• 98-85-1 1-Phenylethanol 
• 100-41-4 ethylbenzene 
• 611-73-4 Benzoylformic acid 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 

Relevant academic research and scientific papers

ZnO nanoparticles: An efficient catalyst for transesterification reaction of α-keto carboxylic esters

Pure ZnO nanoparticles were synthesized by a sustainable precipitation method using zinc nitrate and sodium hydroxide in aqueous medium at room temperature. They were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM-EDX), thermogravimetric analysis (TGA), Fourier transform infrared spectroscopy (FTIR), ultraviolet-visible spectroscopy (UV–vis) spectroscopy and Brunauer-Emmett-Teller (BET) analysis. The XRD patterns indicate the formation of the hexagonal wurtzite phase with high purity and SEM-EDS analysis confirm the purity and a homogenous distribution of the nanostructures. The ZnO nanostructures present plate-like agglomerates, resulting in a quasi-spherical morphology. The catalytic activity of the formed ZnO nanoparticles was evaluated towards the transesterification reaction of different carboxylic esters in the presence of various alcohols. This catalyst is highly selective for the transesterification of α-keto carboxylic ester (methyl benzoylformate) and leads to ca. 97percent of product yield within 24 h of reaction time.

Iron-Catalyzed Esterification of Benzyl C-H Bonds to Form α-Keto Benzyl Esters

An atom-economic and efficient non-precious metal-catalyzed esterification of benzyl C-H bonds has been developed. A variety of α-keto benzyl esters have been accessed in good yields through the reactions between benzyl derivatives and benzoylformic acids using iron trifluoride as a catalyst in the presence of di-tert-butyl peroxide under an inert atmosphere. This strategy provides a straightforward access to linearly expanded α-keto benzyl esters. A plausible reaction mechanism is proposed.