1311434-42-0Relevant articles and documents
Synthesis and biological evaluation of phenolic 4,5-dihydroisoxazoles and 3-hydroxy ketones as estrogen receptor α and β agonists
Poutiainen, Pekka K.,Ven?l?inen, Tuomas A.,Per?kyl?, Mikael,Matilainen, Juha M.,V?is?nen, Sami,Honkakoski, Paavo,Laatikainen, Reino,Pulkkinen, Juha T.
experimental part, p. 3437 - 3447 (2010/10/03)
In this work, 52 diphenyl-4,5-dihydroisoxazoles and -3-hydroxy ketones were prepared and their estrogen receptor α (ERα) and estrogen receptor β (ERβ) activities were explored in order to systematize and maximize their biological activity. The biological