1311446-62-4

Upstream product

• 56341-41-4 5-fluoroindol-2(3H)-one 
• 1311446-60-2 5'-fluoro-2,2-dimethylspiro[cyclopropane-1,3'-indolin]-2'-one 
• 1129-28-8 3-methoxycarbonylbenzyl bromide 
• 1311446-59-9 5-fuoro-3-(propan-2-ylidene)indolin-2-one 

Downstream Products

• 1311445-75-6 3-((5'-fluoro-2,2-dimethyl-2'-oxospiro[cyclopropane-1,3'-indoline]-1'-yl)methyl)benzoic acid 

Relevant academic research and scientific papers

NOVEL CYCLOPROPANE INDOLINONE DERIVATIVES

The present invention relates to a compound of formula (I) as well as pharmaceutically acceptable salt thereof, wherein R1 to R4 have the significance given in claim 1. The compound may be used, for example, for the treatment or prophylaxis of obesity, hyperglycemia, dyslipidemia, and type 1 or type 2 diabetes,

SPIRO INDOLE - CYCLOPROPANE INDOLINONES USEFUL AS AMPK MODULATORS

A compound of formula (I) as well as pharmaceutically acceptable salt thereof, wherein R1 to R4 have the significance given in claim 1, can be used as a modulator of AMPK.

NOVEL CYCLOPROPANE INDOLINONE DERIVATIVES

A compound of formula (I) as well as pharmaceutically acceptable salt thereof, wherein R1 to R4 have the significance given in claim 1, can be used as a medicament.