131148-96-4Relevant academic research and scientific papers
Stereoselective synthesis of α,γ-diamino-β-hydroxy amino acid esters: A new class of amino acids
Reetz,Wunsch,Harms
, p. 371 - 374 (1990)
Isocyano-acetic acid ethylester 3 undergoes a base catalyzed aldol-type addition to N,N-dibenzylamino aldehydes 6 to form oxazolines 7 stereoselectively; these can be ring-opened with NEt3, affording α,γ-diamino-β-hydroxy amino acid esters 2.
