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Ethanone, 2,2,2-trifluoro-1-(4,5,6,7-tetrahydro-1H-indol-2-yl)(9CI) is a chemical compound characterized by the presence of a trifluoromethyl group attached to a tetrahydro-indole ring. This unique structure endows the compound with distinctive properties, making it a valuable building block in pharmaceutical research and development for the synthesis of potential drug candidates. Its potential applications in neuropharmacology are of particular interest, although further research is required to fully explore its capabilities and effects.

131172-58-2

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131172-58-2 Usage

Uses

Used in Pharmaceutical Research and Development:
Ethanone, 2,2,2-trifluoro-1-(4,5,6,7-tetrahydro-1H-indol-2-yl)(9CI) is utilized as a key building block for the synthesis of new drug candidates due to its unique trifluoromethyl group and tetrahydro-indole ring structure. Ethanone, 2,2,2-trifluoro-1-(4,5,6,7-tetrahydro-1H-indol-2-yl)(9CI) is particularly valuable in the design and discovery of drugs targeting various therapeutic areas.
Used in Neuropharmacology:
In the field of neuropharmacology, Ethanone, 2,2,2-trifluoro-1-(4,5,6,7-tetrahydro-1H-indol-2-yl)(9CI) is considered a promising candidate for the development of new pharmacological agents. Its structure and properties suggest potential applications in the treatment of neurological disorders and conditions, although further research is necessary to confirm its efficacy and safety.
Note: Since the provided materials do not specify different industries or application types, the uses are generalized based on the information given. If more specific applications or industries are identified in future research or development, they can be added to the list accordingly.

Check Digit Verification of cas no

The CAS Registry Mumber 131172-58-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,1,7 and 2 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 131172-58:
(8*1)+(7*3)+(6*1)+(5*1)+(4*7)+(3*2)+(2*5)+(1*8)=92
92 % 10 = 2
So 131172-58-2 is a valid CAS Registry Number.

131172-58-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,2,2-trifluoro-1-(4,5,6,7-tetrahydro-1H-indol-2-yl)ethanone

1.2 Other means of identification

Product number -
Other names 2-trifluoroacetyl-4,5,6,7-tetrahydroindole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:131172-58-2 SDS

131172-58-2Relevant academic research and scientific papers

Asymmetric meso-CF3-dipyrromethanes with amino- and heterocyclic functions from trifluoro(pyrrolyl)ethanols and pyrroles

Tomilin, Denis N.,Sobenina, Lyubov N.,Petrova, Olga V.,Sagitova, Elena F.,Budaev, Arsalan B.,Ushakov, Igor A.,Ivanov, Andrey V.,Trofimov, Boris A.

, (2020)

Asymmetric meso-CF3-dipyrromethanes with amino- and nitrogen heterocyclic functions, a new family of the BODIPY dye precursors, have been synthesized in 70–90 % yield by condensation of trifluoro(pyrrolyl)ethanols with pyrroles in the presence of AlCl3. This catalyst, for the first time, was shown to be more efficient than commonly used P2O5, which was entirely inactive in the condensation of pyrroles having basic substituents (amino group and pyrazole moiety).

Hydroxyalkylation of 4,5,6,7-tetrahydroindole with polyfluorocarbonyl compounds as a route to 2-substituted indoles

Sigan, Andrei L.,Gusev, Dmitrii V.,Chkanikov, Nikolai D.,Shmidt, Elena Yu.,Ivanov, Andrei V.,Mihaleva, Al'Bina I.

, p. 5025 - 5028 (2011)

The regioselective hydroxyalkylation of 4,5,6,7-tetrahydroindole at position 2 using highly electrophilic polyfluorocarbonyl compounds was performed for the first time. Oxidation of the products thus formed leads to indoles having 2-hydroxypolyfluoroalkyl and polyfluoroacyl groups.

SYNTHESIS OF PYRROLE-2-CARBOXYLIC ACIDS AND THEIR N-VINYL DERIVATIVES

Sobenina, L. N.,Sergeeva, M. P.,Mikhaleva, A. I.,Sigalov, M. V.,Korostova, S. E.,et al.

, p. 516 - 520 (2007/10/02)

Haloform cleavage of 2-trifluoroacetyl- and N-vinyl-2-trifluoroacetylpyrroles gives pyrrole-2-carboxylic acids and their N-vinyl derivatives in good yields; most of these compounds do not melt between 120-190 deg C, but rather decompose with CO2 evolution.

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