1312005-60-9Relevant academic research and scientific papers
Structure-activity relationships of carboline and carbazole derivatives as a novel class of ATP-competitive kinesin spindle protein inhibitors
Takeuchi, Tomoki,Oishi, Shinya,Watanabe, Toshiaki,Ohno, Hiroaki,Sawada, Jun-Ichi,Matsuno, Kenji,Asai, Akira,Asada, Naoya,Kitaura, Kazuo,Fujii, Nobutaka
, p. 4839 - 4846 (2011/09/20)
The kinesin spindle protein (KSP) is a mitotic kinesin involved in the establishment of a functional bipolar mitotic spindle during cell division. It is considered to be an attractive target for cancer chemotherapy with reduced side effects. Based on natu
