1312031-61-0

Basic information

• Product Name: C₁₆H₂₃ClO₂S
• Synonyms: C₁₆H₂₃ClO₂S
• CAS NO: 1312031-61-0
• Molecular Weight: 314.876
• Mol File: 1312031-61-0.mol

Chemical Properties

• CAS DataBase Reference: C₁₆H₂₃ClO₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₂₃ClO₂S(1312031-61-0)
• EPA Substance Registry System: C₁₆H₂₃ClO₂S(1312031-61-0)

Safety Data

• Hazardous Substances Data: 1312031-61-0(Hazardous Substances Data)

Upstream product

• 123849-08-1 (-)-(R)-dichloromethyl p-tolyl sulfoxide 
• 1312031-60-9 C₁₈H₂₅ClO₃S 
• 99440-40-1 ethyl (E)-2-methyl-2-heptenoate 

Relevant articles and documents

The first example for the asymmetric synthesis of allenes by the Doering-LaFlamme allene synthesis with enantiopure cyclopropylmagnesium carbenoids

The reaction of lithium α-sulfinyl carbanion of enantiopure dichloromethyl p-tolyl sulfoxide with α,β-unsaturated carbonyl compounds gave optically active 1-chlorocyclopropyl p-tolyl sulfoxides having a carbonyl group with high asymmetric induction from the sulfur chiral center. Reduction of the carbonyl group followed by treatment with Grignard reagent, the 1-chlorocyclopropyl p-tolyl sulfoxides resulted in the formation of enantiopure allenic alcohols via the Doering-LaFlamme-type rearrangement of enantiopure cyclopropylmagnesium carbenoid intermediates. This is the first example for the asymmetric synthesis of allenes by the Doering-LaFlamme allene synthesis.