1312080-58-2

Upstream product

• 1312080-34-4 (R,E)-2,6-dimethylundec-6-en-10-yne-2,3-diol 
• 20445-31-2 R-(+)-α-trifluoromethyl-α-methoxy-phenylacetic acid 
• 22850-55-1 (E)-6,10-dimethyl-5,9-undecadien-1-yne 
• 5389-87-7 1-chloro-3,7-dimethylocta-2,6-diene 

Relevant academic research and scientific papers

Total synthesis of the protein phosphatase 2A inhibitor lactodehydrothyrsiferol

Cascading epoxides: The squalene-derived polyether lactodehydrothyrsiferol (1) has been prepared through a convergent sequence that features an epoxide-opening cascade to construct the tetrahydrofuran and tetrahydropyran subunits. Additional features include a stereodivergent diene diepoxidation, a monodeoxygenation of a triol, and complex fragment couplings through Suzuki and Nozaki-Hiyama-Kishi reactions. Copyright