131216-48-3

Basic information

• Product Name: 1-iodo-1-(trimethylsilyl)-3-phenylpropane
• CAS NO: 131216-48-3
• Molecular Weight: 318.273
• Mol File: 131216-48-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-iodo-1-(trimethylsilyl)-3-phenylpropane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-iodo-1-(trimethylsilyl)-3-phenylpropane(131216-48-3)
• EPA Substance Registry System: 1-iodo-1-(trimethylsilyl)-3-phenylpropane(131216-48-3)

Safety Data

• Hazardous Substances Data: 131216-48-3(Hazardous Substances Data)

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 1450-14-2 1,1,1,2,2,2-hexamethyldisilane 

Downstream Products

• 27066-35-9 (E)-1,4-diphenylbut-1-ene 
• 70388-65-7 (Z)-1,4-diphenyl-1-butene 

Relevant articles and documents

Triply Convergent, Stereospecific Alkene Formation via Peterson Olefination

α-Iodo silanes 8 were prepared from α-hydroxy silanes and after halogen/metal exchange and treatment with copper(I)bromide-dimethyl sulfide were coupled with acid chlorides to yield α-silyl ketones 2.Cram controlled addition with a variety of nucleophiles followed by treatment with acid or base led to either the (E)- or (Z)-alkene in good overall yields from the iodide (47-67percent) and with excellent stereoselectivities (>95/95/5 isomeric purity.