1312166-08-7

Upstream product

• 176853-39-7 7-<β-trans-(N,N-dimethylamino)ethenyl>-8-nitroquinoline 
• 7471-63-8 8-nitro-7-methylquinoline 
• 931-15-7 (1S,2S)-trans-2-aminocyclohexanol 
• 181285-05-2 methyl 8-aminoquinoline-7-carboxylate 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 

Relevant academic research and scientific papers

DIHYDROPYRIDO QUINAZOLINE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS

Disclosed herein are compounds of formula (I), which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases, in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor.

PYRIDOQUINAZOLINONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS

The present invention is directed to quinolinone-pyrazolone compounds of formula (I) which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor.