131225-70-2Relevant academic research and scientific papers
Enantioselective Oxidative Rearrangements with Chiral Hypervalent Iodine Reagents
Brown, Michael,Kumar, Ravi,Rehbein, Julia,Wirth, Thomas
supporting information, p. 4030 - 4035 (2016/03/16)
A stereoselective hypervalent iodine-promoted oxidative rearrangement of 1,1-disubstituted alkenes has been developed. This practically simple protocol provides access to enantioenriched α-arylated ketones without the use of transition metals from readily
Synthesis and biological activity of new diarylalkenes
Golebiewski,Wilkowska
, p. 759 - 766 (2007/10/03)
Condensation of 5-nitro-, 3-chloro-, and 5-chlorosalicylic acids with formaldehyde afforded dimeric disalicylmethanes, which were O-methylated with dimethyl sulfate and oxidized with chromium(VI) oxide to diarylketones 9, 10, 11, 12. Wittig reaction with
Synthesis and biological activity of new diarylalkenes
Golebiewski, W. Marek,Cieniecka-Ros?onkiewicz,Szybinska
, p. 26 - 30 (2007/10/03)
Condensation of 5-nitro-, 3-chloro-, and 5-chlorosalicylic acid with formaldehyde afforded dimeric disalicylmethanes which were O-methylated with dimethyl sulfate and oxidized with chromium(VI) oxide to give the diarylketones 10, 11, 12. Wittig reaction with ylides obtained by deprotonation of alkyltriphenylphosphonium salts with sodium bis (trimethylsilyl)amide yielded a series of diarylalkenes. Some of the obtained compounds showed high antimicrobial activity in vitro against Bacillus subtilis and Mycobacterium smegmatis.
