1312295-07-0Relevant academic research and scientific papers
Chiral Br?nsted Acid Catalyzed Enantioselective aza-Friedel-Crafts Reaction of Cyclic α-Diaryl N-Acyl Imines with Indoles
Glava?, Danijel,Zheng, Chao,Dokli, Irena,You, Shu-Li,Gredi?ak, Matija
, p. 8752 - 8760 (2017)
Asymmetric addition of indoles to cyclic α-diaryl-substituted N-acyl imines, which are generated in situ from 3-aryl 3-hydroxyisoindolinones, is described. The transformation proceeds smoothly with a broad range of indoles and isoindolinone alcohols using
Organocatalyzed Enantioselective Synthesis of Quaternary Carbon-Containing Isoindolin-1-ones
Yu, Xiaolei,Wang, Youming,Wu, Guiping,Song, Haibin,Zhou, Zhenghong,Tang, Chuchi
experimental part, p. 3060 - 3066 (2011/06/28)
3,3′-Triphenylsilyl-substituted (S)-BINOL-based (1,1′-bi-2- naphthol phosphoric acid has proven to be an effective organocatalyst for the asymmetric Friedel-Crafts alkylation of indoles with 3-substituted 3-hydroxyisoindolin-1-ones, affording the correspo
