1312312-89-2

Upstream product

• 1312312-87-0 methyl 5-(4-hydroxyphenyl)-pyridine-2-carboxylate 
• 2823-44-1 2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl fluoride 

Downstream Products

• 1312312-93-8 5-[4-(α-D-mannopyranosyloxy)phenyl]-picolinic acid 
• 1312312-91-6 methyl 5-[4-(α-D-mannopyranosyloxy)phenyl]-2-pyridinecarboxylate 

Relevant academic research and scientific papers

MANNOSE PHOSPHATE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION

Compounds of the formula (I) (I) wherein n is 0, 1 or 2, R1 is aryl, heteroaryl or heterocyclyl, and R2 and R3 are, independent of each other, hydrogen or a substituent as described in the specification, and one of RA, RB, RC and RD is P02(OH)2 and the other ones are hydrogen; are orally available medicaments useful for the prevention and treatment of bacterial infections, in particular of urinary infections caused by E. coli.

MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION

Compounds of the formula (I) wherein n is 0, 1 or 2, R1 is aryl, heteroaryl or heterocyclyl, and R2 and R3 are hydrogen or a substituent as described in the specification, are useful for the prevention and treatment of bacterial infections, in particular of urinary infections caused by E. coli.