1312343-50-2Relevant articles and documents
Sp3 C-H bond activation with ruthenium(II) catalysts and C(3)-alkylation of cyclic amines
Sundararaju, Basker,Achard, Mathieu,Sharma, Gangavaram V. M.,Bruneau, Christian
, p. 10340 - 10343 (2011/08/05)
A selective C(3)-alkylation via activation/functionalization of sp 3 C-H bond of saturated cyclic amines was promoted by (arene)ruthenium(II) complexes featuring a bidentate phosphino-sulfonate ligand upon reaction with aldehydes. This highly regioselective sustainable transformation takes place via initial dehydrogenation of cyclic amines and hydrogen autotransfer processes.