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1312446-16-4

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1312446-16-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1312446-16-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,2,4,4 and 6 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1312446-16:
(9*1)+(8*3)+(7*1)+(6*2)+(5*4)+(4*4)+(3*6)+(2*1)+(1*6)=114
114 % 10 = 4
So 1312446-16-4 is a valid CAS Registry Number.

1312446-16-4Downstream Products

1312446-16-4Relevant academic research and scientific papers

Synthesis and SAR study of tricyclic sulfones as γ-secretase inhibitors: C-6 and C-8 positions

Su, Jing,Tang, Haiqun,McKittrick, Brian A.,Xu, Ruo,Clader, John W.,Greenlee, William J.,Hyde, Lynn,Zhang, Lili

, p. 3447 - 3451 (2011/07/07)

SAR exploration at C-6 and C-8 positions of the tricyclic sulfone series was carried out. Several functional groups were found to be well tolerated at C-6 and C-8 positions. Selective combination of C-6 and C-8 modification resulted in new tricyclic sulfone analogs with efficacy in in vivo mouse Aβ40 lowering model.

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