1312451-16-3Relevant academic research and scientific papers
Synthesis and computational analysis of densely functionalized triazoles using o -nitrophenylalkynes
McIntosh, Melissa L.,Johnston, Ryne C.,Pattawong, Ommidala,Ashburn, Bradley O.,Naffziger, Michael R.,Cheong, Paul Ha-Yeon,Carter, Rich G.
experimental part, p. 1101 - 1112 (2012/03/11)
Dipolar cylcoadditions with azides using a series of o-nitrophenylethynes and disubstituted alkynes were studied experimentally and computationally. Density functional theory computations reveal the steric and electronic parameters that control the regios
Rapid, robust, clean, catalyst-free synthesis of 2-halo-3-carboxyindoles
Kunzer, Aaron R.,Wendt, Michael D.
supporting information; experimental part, p. 1815 - 1818 (2011/05/05)
A novel synthesis of 2-halo-3-carboxyindoles from 2-(2,2-dihalovinyl) anilines was discovered. Reaction conditions and substrate applicability were studied. Optimally, the reaction takes only minutes when these substrates are heated in DMSO at 120 °C in t
