1312466-07-1

Basic information

• Product Name: 6-chloro-5-phenylpyrimidine-4-(9-O-quinidine) ether
• Synonyms: 6-chloro-5-phenylpyrimidine-4-(9-O-quinidine) ether
• CAS NO: 1312466-07-1
• Molecular Weight: 513.039
• Mol File: 1312466-07-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-chloro-5-phenylpyrimidine-4-(9-O-quinidine) ether(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-5-phenylpyrimidine-4-(9-O-quinidine) ether(1312466-07-1)
• EPA Substance Registry System: 6-chloro-5-phenylpyrimidine-4-(9-O-quinidine) ether(1312466-07-1)

Safety Data

• Hazardous Substances Data: 1312466-07-1(Hazardous Substances Data)

Upstream product

• 1312466-27-5 4,6-dichloro-2-(methylsulfonyl)-5-phenylpyrimidine 
• 64415-11-8 4,6-dichloro-2-methylthio-5-phenylpyrimidine 
• 3974-16-1 4,6-dichloro-5-phenyl-pyrimidine 
• 56-54-2 quinidine 

Relevant articles and documents

Asymmetric total syntheses of (-)-variabilin and (-)-glycinol

Total syntheses of (-)-variabilin and (-)-glycinol have been accomplished, using the catalytic, asymmetric "interrupted" Feist-Benary reaction (IFB) as the key transformation to introduce both stereogenic centers. A monoquinidine pyrimidinyl ether catalyst affords the IFB products in over 90% ee in both cases. Other key steps include an intramolecular Buchwald-Hartwig coupling and a nickel-catalyzed aryl tosylate reduction.